USING MIXED-METHODS RESEARCH TO STUDY COPING STRATEGIES AMONG COLORECTAL CANCER PATIENTS



Nuclear factor erythroid 2-related factor 2 promotes radioresistance by regulating glutamate-cysteine ligase modifier subunit and its unique immunoinvasive pattern

The enzyme glutamate-cysteine ligase modifier subunit (GCLM) serves as the initial rate-limiting factor in glutathione (GSH) synthesis.GSH is the preferred substrate for glutathione peroxidase 4 (GPX4), directly impacting its activity and stability.This study aims to elucidate the expression of GCLM and its correlation with the nuclear factor eryth

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Upregulation of Lactobacillus spp. in gut microbiota as a novel mechanism for environmental eustress-induced anti-pancreatic cancer effects

Pancreatic ductal adenocarcinoma (PDAC) is a highly lethal malignancy with limited effective treatment options.Emerging evidence links enriched environment (EE)-induced eustress to PDAC inhibition.However, the underlying mechanisms remain unclear.In this study, we explored the role of gut microbiota in PDAC-suppressive effects of EE.We demonstrated

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